Williams Hematology: Red Cell and Its Diseases

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Autor: Josef Prchal, Marshall Lichtman

ISBN: 9781264269075

Editura: McGraw-Hill

Anul publicării: 2022

Pagini: 608

Categoria: Hematology

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DESCRIERE

A comprehensive, much-needed clinical guide to red cell disorders

Red blood cell (RBC) disorders are conditions that affect the red blood cells. When red blood cells do not have enough hemoglobin, oxygen cannot reach all parts of the body—as a result, organs start to malfunction and may lead to a host of issues including deformities, enlarged spleen, heart problems and other diseases. The Red Cells and its Diseases provides clinicians with a practical diagnostic and treatment framework for identifying and successfully managing acute, congenital, and chronic red blood cell disorders. This comprehensive, yet concise resource covers the structure and physiology of the red cell, classification of red cell disease, diseases of red cell production, the causes of anemia, red cell transfusion, and more.

Market: Hematologists-oncologists (15, 000 US; 25, 000 global), internal medicine (114, 087), internal medicine/pediatrics (4, 840), medical students (3rd year/4th year) (20, 000), nurse practitioners (270, 000), physician assistants (140, 000)
Fills a gap in the literature on red cell disorders
Provides new foundations for development of therapy for red cell diseases
Includes classifications, etiology and pathogenesis, clinical and laboratory features, differential diagnosis, treatment, management, and supportive care

Part 1. Structure and Physiology of the Red Cell

Chap. 1 Structure of the Red Cell

Chap 2. Erythropoiesis and Red Cell turnover

Part 2. Classification of Red cell Diseases

Chap. 3. Clinical Manifestations and Classification of Red

Cell Disorders

Part 3. Diseases of Red Cell Production

Chap 4. Aplastic Anemia

Chap 5. Erythroid Aplasia

Chap 6. Anemia of Chronic Inflammation

Chap 7. Erythropoietic effects of endocrine disorders

Chap 8. Paroxysmal nocturnal hemoglobinuria

Chap 9. Folate, Cobalamin and the megaloblastic anemia

Chap 10. Iron Metabolism

Chap. 11. Iron deficiency anemia

Chap 12. Anemia resulting from other nutritional

deficiencies

Chap 13. Anemia associated with marrow infiltration

Part 4. Anemias as a result principally of inherited

disorders

Chap 14. Congenital (inherited) dyserythropoietic anemias

Chap 15. Erythrocyte membrane disorders

Chap 16. Erythrocyte Enzyme disorders

Chap 17. The thalassemias

Chap 18. Disorders of hemoglobin structure: Sickle cell

anemia and related abnormalities

Chap 19. Methemoglobinemia and other

dyhemoglobinemias

Chap 20. Polyclonal hereditary and acquired sideroblastic

anemia

Chap 21. The porphyrias

Part 5. Anemia as a result of exogenous factors

Chap 22. Fragmentation hemolytic anemia

Chap 23. Erythrocyte disorders as a result of chemicals,

metals, and other toxic agents

Chap 24. Hemolytic anemia as a result of infections with

microorganisms

Chap 25. Hypersplenism and hyposplenism

Chap 26. Immune hemolytic anemia

Chap 27. Alloimmune hemolytic disease of the fetus and

newborn

Part 6. Erythrocytosis

Chap 27. Primary and secondary erythrocytosis

Part 7. Red Cell Transfusion

Chap 28. Erythrocyte antigens and antibodies

Chap 29. Blood procurement and red cell transfusion

Marshall A. Lichtman, MD, is dean emeritus, and a former professor of medicine, biochemistry, and biophysics at the University of Rochester Medical Center in New York. He is a past president of the American Society of Hematology (ASH).

Josef T. Prchal, MD, is a professor in the division of hematology and hematologic malignancies, a Huntsman Cancer Institute investigator, and a member of the Cell Response and Regulation Program and the Imaging, Diagnostics, and Therapeutics Program at the University of Utah.