Neuro-Oncology Compendium for the Boards and Clinical Practice

Renowned experts in the neuro-oncological field bring their expertise together for Neuro-Oncology Compendium for the Boards and Clinical Practice. This volume reviews the core topics of neuro-oncology including adult and pediatric neuro-oncology, management, central nervous system tumor complications, genetic considerations, and more. With a focus on updated treatments and terminology, this volume is designed to comprehensively review all major facets of neuro-oncology so that physicians-in-training may prepare for the board review and practicing specialists can stay up to date in their treatment of patients.

This essential text includes hundreds of figures and tables, succinct review flashcards, end-of-chapter questions and answers, as well as end-of-volume exams so readers can review and test their own comprehension. Each chapter has been reviewed by the editors to ensure cohesive board-level verbiage, emphasizing practical clinical knowledge. Neuro-Oncology Compendium for the Boards and Clinical Practice is up-to-date and comprehensive, eliminating the need for multiple sources of study.

Key features of this volume include:
-End of chapter flashcards to summarize key content
-End of chapter Questions and Answers for review
-Practice exams to simulate board questions
-Updated terminology and practices
-Complimentary images and tables to support learning

• More than 30 specialists authoring focused chapters
• High-yield summaries at the end of each chapter
• Questions and Answers at the end of each chapter
• Practice exams at the end of the text

Neuro-Oncology Overview
1. Neuropathology Primer
2. Imaging of Central Nervous System Tumors
Adult Neuro-Oncology
3. Glioblastoma
4. Diffuse Glioma
5. Meningioma
6. Ependymoma
7. Tumors of the Pituitary Gland
8. Germ Cell Tumors
9. Intraventricular Tumors
10. Rare Tumors in Adults, including Medulloblastoma
11. Primary Central Nervous System Lymphoma and Hematopoietic Neoplasms affecting the Nervous System
12. Metastatic disease in the Central Nervous System
13. Tumors Affecting the Spinal Cord
Pediatric Neuro-Oncology
14. Epidemiology and General Overview of Pediatric Central Nervous System Tumors
15. Neurosurgical Management of Pediatric Central Nervous System Tumors
16. Pediatric Embryonal Tumors
17. Pediatric Low Grade Glioma
18. Pediatric High Grade Glioma
Management of Neuro-Oncologic disease
19. Neurosurgical Management of Adult Central Nervous System Tumors
20. Radiotherapy in Neuro-oncology
21. Principles of Systemic Therapy in Neuro-Oncology
22. Device-based Treatments in Neuro-Oncology
Complications of Systemic and Central Nervous System Cancers
23. Neurologic Complications in Cancer Patients
24. Paraneoplastic Neurological Syndromes
25. Neuro-Oncologic Emergencies
Genetics and Neuro-Oncologic Disease
26. Familial Cancer Syndromes
27. The Neurofibromatoses
Special Considerations in Neuro-Oncology
28. Designing and Deciphering Clinical Trials: Methodological ingredients to nourish a healthy study
29. Procedures and Well-Care Clinics in Neuro-Oncology: Roles for Advanced Practice Providers
30. Neuro-Oncology in the Elderly
31. Palliative Care in Neuro-Oncology
32. The Neuro-Oncology of Women (N. O. W.)

Maciej M. Mrugala, Na Tosha Gatson, Jennifer L. Clarke, Sylvia C. Kurz, and Kathryn S. Nevel

Maciej M. Mrugala, MD, PhD Neuro-oncologist, Mayo Clinic Cancer Center Professor of Medicine, Comprehensive Neuro-Oncology Program and Neuro-Oncology Fellowship Program Chair of the Neuro-Oncology Section of the American Academy of Neurology Na Tosha N. Gatson, MD, PhD, FAAN Medical Director, Neuro-Oncology Banner MD Anderson Cancer Center Associate Professor of Medicine and Neurology University of Arizona College of Medicine Sylvia Kurz, MD PhD Interim Director, Neuro-Oncology Program Brain and Spine Tumor Center, Laura and Isaac Perlmutter Cancer Center New York University Langone Health Kathryn S. Nevel, MD Assistant Professor of Clinical Neurology Indiana University Health and Indiana University School of Medicine Brain Tumor Center, Indiana University Health Jennifer L. Clarke, MD, MPH Professor of Clinical Neurology and Neurological Surgery UCSF Weill Institute of Neurosciences Division of Neuro-oncology, University of California, San Francisco Member, UCSF

Helen Diller Family Comprehensive Cancer Center

Contributors:

Harood Ahmad, MD
University of Maryland, School of Medicine
Baltimore, MD, USA

Iyad Alnahhas, MD
Thomas Jefferson University
Philadelphia, PA, USA

Nikolaos Andreatos, MD
Mayo Clinic
Rochester, MN, USA

Ashok R. Asthagiri, MD
University of Virginia
Charlottesville, VA, USA

Amir Azadi, MD
Banner MD Anderson Cancer Center
Gilbert, AZ, USA

Molly Havard Blau, MD, MS
University of Washington
Seattle, WA, USA

Maria L. Boccia, PhD, LM
Baylor University Robbins College of Health and Human Sciences
Waco, TX, USA

Adrienne A. Boire, MD, PhD
Memorial Sloan Kettering Cancer Center
New York, NY, USA

Cameron Brimley, MD
Geisinger Neuroscience Institute
Danville, PA, USA

Alyssa Callela, PA- C
Geisinger Neuroscience and Cancer Institutes
Danville, PA, USA

Jennifer L. Clarke, MD, MPH
University of California
San Francisco, CA, USA

Andrew R. Conger, MD, MS />Geisinger Health System
Danville, PA, USA

Scott L. Coven, DO, MPH
Riley Hospital for Children at IU Health
Indianapolis, IN, USA

Kara L. Curley, PA-C
Mayo Clinic
Phoenix, AZ, USA

Logan S. DeWitt, DO
Indiana University School of Medicine
Indianapolis, IN, USA

Radhika Dhamija, MD
Mayo Clinic
Phoenix, AZ, USA

Richard S. Dowd, MD, MS
Tufts Medical Center
Boston, MA, USA

Reginald Fong, MD
Geisinger Medical Center
Danville, PA, USA

Ekokobe Fonkem, DO
Baylor Scott and White
Texas A&M University and Baylor College of Medicine
Temple, TX, USA

Morgan Freret, MD, PhD
Memorial Sloan Kettering Cancer Center
New York, NY, USA

Shobhit Kumar Garg, MD, FRCR
William Harvey Hospital,
East Kent Hospitals University Foundation Trust
Ashford, Kent, UK

Na Tosha N. Gatson, MD, PhD, FAAN
Banner MD Anderson Cancer Center
Phoenix, AZ, USA
Geisinger Health
Danville, PA, USA

Pierre Giglio, MD
The Ohio State University
Columbus, OH, USA

Michael Glantz, MD
Penn State College of Medicine - Milton S. Hershey Medical Center
Hershey, PA, USA

Andrew J. Gogos, MBBS, FRACS
St Vincents Hospital Melbourne
Fitzroy, AU

David Gritsch, MD
Mayo Clinic College of Medicine and Science Residency, Neurology
USA

Simon Gritsch, MD, PhD
University of Heidelberg
Germany

Lia M. Halasz, MD
University of Washington
Seattle, WA, USA

Shawn L. Hervey- Jumper, MD
University of California San Francisco
San Francisco, CA, USA

Joseph M. Hoxworth, MD
Mayo Clinic
Phoenix, AZ, USA

Maya Hrachova, DO
University of Oklahoma
Oklahoma City, OK, USA

V. Internò, MD
University of Bari "Aldo Moro"
Bari, IT

Rajan Jain
New York University Grossman School of Medicine
New York, NY, USA

George I. Jallo, MD
Johns Hopkins All Children's Hospital
St. Petersburg, FL, USA

Thomas J. Kaley, MD
Memorial Sloan Kettering Cancer Center
New York, NY, USA

Matthias Karajannis, MD, MS
Memorial Sloan Kettering Cancer Center
New York, NY, USA

John M. Kindler, MD
Indiana University School of Medicine
Indianapolis, IN, USA

Peter Kobalka, MD
Ohio State University
Columbus, OH, USA

Ibrahim Kulac, MD
Koç University School of Medicine
Istanbul, Turkey

Erika N. Leese, PA- C
Geisinger Medical Center
Danville, PA, USA

Mary Jane Lim- Fat
Geisinger Medical Center
Danville, PA, USA

Rimas V. Lukas, MD
Northwestern University
Chicago, IL, USA

Alireza Mansouri, MD, MSc, FRCSC
Penn State Health
Hershey, PA, USA

Aaron Mochizuki, DO
Cincinnati Children's Hospital Medical Center
Cincinnati, OH, USA

J. M. Mohamud, DO
Indiana University
Indianapolis, IN, USA

Ramin A. Morshed, MD
University of California San Francisco
San Francisco, CA, USA

Maciej M. Mrugala, MD, PhD, MPH
Mayo Clinic
Phoenix, AZ, USA

Lakshmi Nayak, MD
Dana-Farber Cancer Institute, Harvard Medical School
Boston, MA, USA

Matthew T. Neal, MD, MBA
Mayo Clinic
Phoenix, AZ, USA

K. S. Nevel
Indiana University School of Medicine
Indianapolis, IN, USA

Theodore Nicolaides

Mohammad Hassan A. Noureldine, MD, MSc
University of South Florida
Tampa, FL, USA

Samanthalee C. S. Obiorah, BSc
Warren Alpert Medical School of Brown University
Providence, RI, USA

Shirley Ong, MD
The Ohio State University Wexner Medical Center
Columbus, OH, USA

Sonia Partap, MD
Stanford University
Palo Alto, CA, USA

David M. Peereboom, MD
Burkhardt Brain Tumor and Neuro- Oncology Center
Neurological Institute
Cleveland Clinic, Cleveland, OH, USA

Melike Pekmezci, MD
University of California
San Francisco, CA, USA

Katherine B. Peters, MD, PhD, FAAN
Preston Robert Tisch Brain Tumor Center, Duke University School of Medicine
Durham, NC, USA

Sheetal Phadnis, MD
University of Alabama
Birmingham, AL, USA

Scott R. Plotkin, MD, PhD
Massachusetts General Hospital
Boston, MA, USA

Vinay K. Puduvalli, MD
UT MD Anderson Cancer Center
Houston, TX, USA

Appaji Rayi, MD
Charleston Area Medical Center Health System
Charleston, WV, USA

Alexander Ropper
Baylor College of Medicine
Houston, TX, USA

R. Rudà
San Giovanni Battista Hospital and University of Torino
Torino, IT

Sameer Farouk Sait, MBBS
Memorial Sloan Kettering Cancer Center
New York, NY, USA

David Schiff, MD
University of Virginia Health System
Charlottesville, VA, USA

Nir Shimony, MD
Geisinger Medical Center
Danville, PA, USA

Kevin Shiue, MD
Indiana University School of Medicine
Indianapolis, IN, USA

Wayne Slone, MD

R. Soffietti, MD
University
Turin, IT

Kun- Wei Song, MD
Massachusetts General Hospital / Dana-Farber Cancer Institute
Boston, MA, USA

Ramya Tadipatri, MD
Barrow Neurological Institute
Phoenix, AZ, USA

Hirokazu Takami, MD, PhD
University of Tokyo
Tokyo, Japan

Kerianne R. Taylor, RN
Banner MD Anderson Cancer Center
Phoenix, AZ, USA

Steven A. Toms, MD, MPH
Brown University / Lifespan Health System
Providence, RI, USA

Cristina Valencia- Sanchez, MD, PhD
Mayo Clinic Arizona
Scottsdale, AZ, USA

Terrence Verla
Baylor College of Medicine
Houston, TX, USA

Gordon A. Watson, MD, PhD
Indiana University School of Medicine
Indianapolis, IN, USA

Jessica A. Wilcox, MD
Memorial Sloan Kettering Cancer Center
New York, NY, USA

Terri L. Woodard, MD, MPH
Baylor University College of Medicine
Houston, TX, USA

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