Molecular and Clinical Pathology of Neurodegenerative Disease

PRP: 469,20 lei

Diferență: 23,46 lei

Disponibilitate: la comandă (vezi secțiunea "Despre livrare")

adaugă în coș

Autor: Patrick Lewis, Jennifer Spillane

ISBN: 9780128110690

Editura: Elsevier Academic Press

Anul publicării: 2019

Pagini: 274

download

DESCRIERE

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration.

Provides an up-to-date summary of neurodegeneration at a molecular, cellular, and tissue level for the most common human disorders
Describes the clinical background and underlying molecular processes for Alzheimer’s disease, Parkinson’s, Prion, Motor Neuron, Huntington’s, and Multiple Sclerosis
Highlights the state-of-the-art treatment options for each disorder
Details examples of relevant cutting edge experimental systems, including genome editing and human pluripotent stem cell-derived neuronal models

1. An Introduction to Neurodegeneration
2. Alzheimer’s Disease and Dementia
3. Parkinson’s Disease
4. The Prion Diseases
5. The Motor Neuron Diseases and Amyotrophic Lateral Sclerosis
6. Huntington’s Chorea
7. Multiple Sclerosis

By Patrick A. Lewis, University of Reading, and UCL Institute of Neurology, UK and Jennifer E. Spillane, National Hospital for Neurology and Neurosurgery, UK