Hypertension (Oxford Cardiology Library)

The management of hypertension varies considerably from clinician to clinician. This pocketbook is a concise and evidence-based summary of current understanding and practice, including the most up-to-date guidance from national and international bodies and their recommendations for hypertension care.

Written by an international team of experts, it covers all the key aspects of hypertension from epidemiology and aetiology to investigations, management, and complications. It also covers the management of hypertension in special patient groups such as in pregnancy and the elderly. Emphasis is laid throughout the book on lowering cardiovascular risk as a part of managing hypertension. An essential tool for everyday use in managing hypertension, this book aids clinical decision-making by collating all the relevant information and guidance in one easily accessible place.

This new edition has been fully updated to include expanded content on hypertension mediated organ damage and two new chapters covering the effects of hypertension on the brain and on the eyes.

Part 1: Epidemiology, pathogenesis and diagnosis
1: Epidemiology of hypertension, Sunil K. Nadar and Stephanie Harrison
2: Pathophysiology of hypertension, Sheon Mary, Giacomo Rossitto, and Christian Delles
3: Secondary hypertension, Gurbhej Singh and Gurpreet Wander
4: Diagnosis and investigation of hypertension, Martin Wolley and Michael Stowasser
Part 2: Complications of hypertension
5: Hypertension: a cardiovascular risk factor, Thomas Salmon, James Hatherley, and Rajiv Sankaranarayanan
6: Left ventricular hypertrophy, Yuichiro Yano and Sunil K. Nadar
7: Atrial fibrillation and hypertension, Mohammed Najeeb Al-Rawahi
8: The brain in Hypertension, Arun R. Gujjar
9: The kidneys in hypertension, Sarah Ahmad and Jordana B. Cohen
10: The eye in hypertension, Peck Lin Lip
Part 3: Management of hypertension
11: Overview of the guidelines on the management of hypertension, Gregory Y. H. Lip and Sunil K. Nadar
12: Hypertension and cardiovascular risk management, James P. Sheppard and Sunil K. Nadar
13: Non-pharmacological management of hypertension, Benjamin J. R. Buckley and Stephanie J. Finnie
14: Diuretics in hypertension, Harsh Goel and Ashish Kumar
15: Beta blockers in hypertension, Hatim Al Lawati
16: Calcium channel blockers and hypertension, Stefanie Lip and Sandosh Padmanabhan
17: Blockers of the Renin- Angiotensin- Aldosterone system in hypertension, Ify R. Mordi and Chim C. Lang
18: Other antihypertensive agents, Shankar Patil, Muzahir Tayebjee, and Sunil K. Nadar
19: Renal denervation, Vikas Kapil
20: Improving medication adherence in hypertension, Hassan Al-Riyami and Dierdre A. Lane
Part 4: Special conditions
21: Hypertension in pregnancy: Physiopathological, preventive, therapeutic and long-term considerations, Gloria Valdés
22: Hypertensive emergencies, Alena Shantsila
23: Treatment of the older adult, Asangaedem Akpan
24: Diagnosis and management of resistant hypertension, Fang-Fei Wei, Chen Liu, and Jan A. Staessen
25: Hypertension in patients with diabetes mellitus, Daniel J. Cuthbertson

Edited by Sunil Nadar, Senior Consultant Cardiologist, Sultan Qaboos University Hospital, Muscat, Oman, and Gregory Lip, Price-Evans Chair of Cardiovascular Medicine, University of Liverpool, Liverpool, UK

Sunil K Nadar is a Consultant Cardiologist at Sultan Qaboos University Hospital in Muscat, Oman. Prior to this he worked as a Consultant Cardiologist at the NHS in Birmingham, UK. He did his research MD on platelet activation in hypertension and completed his specialist cardiology training in the West Midlands, UK. Dr Nadar is a Co-Editor with the Journal of Human Hypertension and an Associate Editor with the Sultan Qaboos University Medical Journal. He is currently involved in research work investigating the effects of thalassemia on the heart, the psychological impact of admission on patients with heart disease, and community awareness of the dangers of high dietary salt intake. He is also the coordinator for the May Measurement Month programme in Oman.

Gregory Y. H. Lip, is Price-Evans Chair of Cardiovascular Medicine at the University of Liverpool and Director of the Liverpool Centre for Cardiovascular Science at the University of Liverpool and Liverpool Heart & Chest Hospital, UK. He is also Distinguished Professor at Aalborg University, Denmark, and Adjunct Professor at Seoul National University and Yonsei University, Seoul, Korea. In 2014 Professor Lip was ranked by Expertscape as the world's leading expert in the understanding and treatment of Atrial Fibrillation. He was on the writing committee for various international guidelines and has acted at a senior editorial level for major international textbooks and journals. Professor Lip's current research interests range from epidemiology to pathophysiology, translational research, clinical risk assessment and trajectories of risk, patient management pathways, and applied health research.

Contributors:

Sarah Ahmad
Renal-Electrolyte and Hypertension Division,
Department of Medicine,
Perelman School of Medicine, University of Pennsylvania,
Philadelphia, USA

Asangaedem Akpan
Consultant Geriatrician, Liverpool University Hospitals NHS FT
Visiting Professor, University of Cumbria
Honorary Associate Professor, University of Liverpool
Ageing Specialty Research Group Lead CRN NWC
Liverpool UK

Hatim Al-Lawati
Senior consultant cardiologist
Department of Medicine
Sultan Qaboos University Hospital,
Muscat, Oman

Mohamed Najeeb Al-Rawahi
Consultant Cardiac electrophysiologist
Sultan Qaboos University Hospital,
Muscat, Oman
And
Department of Cardiology,
National Heart Center
Muscat, Oman

Hassan Al-Riyami
Head Nurse Cardiac Catheter lab and Interventional radiology
Directorate of Nursing
Sultan Qaboos University Hospital
Muscat, Oman

Benjamin J. R. Buckley
Research Fellow,
Liverpool Centre for Cardiovascular Science,
University of Liverpool and Liverpool Heart & Chest Hospital,
Liverpool, UK

Jordana B. Cohen
Assistant Professor of Medicine and Epidemiology
Renal-Electrolyte and Hypertension Division
Center for Clinical Epidemiology and Biostatistics
Perelman School of Medicine, University of Pennsylvania
Philadelphia, USA

Daniel J. Cuthbertson
Department of Diabetes and Endocrinology,
Liverpool University Hospitals NHS Foundation Trust
University of Liverpool
Liverpool, UK

Christian Delles
Institute of Cardiovascular & Medical Sciences
BHF Glasgow Cardiovascular Research Centre
University of Glasgow
Glasgow, UK

Stephanie J. Finnie
Trust Grade Doctor,
Department of Medicine,
Royal Liverpool University Hospital,
Liverpool, UK

Arunodaya R. Gujjar
Professor of Neurology,
Department of Medicine (Neurology),
College of Medicine and Health Sciences,
Sultan Qaboos University,
Muscat, Oman

Stephanie Harrison
Liverpool Centre for Cardiovascular Science
University of Liverpool,
Liverpool UK

James Hatherley
Department of Medicine
Liverpool University Hospital Foundation trust
Liverpool, UK

Vikas Kapil
Senior Lecturer and Consultant Physician
Clinical Pharmacology & Cardiovascular Medicine
Barts BP Centre of Excellence,
St Bartholomew's Hospital, Barts Health NHS Trust,
London, UK
And
Centre for Cardiovascular Medicine and Devices,
William Harvey Research Institute,
Queen Mary University
London, UK

Ashish Kumar
Department of Medicine,
Wellspan York Hospital,
York, PA, USA
And
Clinical Assistant Professor of Medicine,
Sidney Kimmel Medical College at Thomas Jefferson University,
Philadelphia, PA, USA

Deirdre Lane
Reader in Cardiovascular medicine
Liverpool Centre for Cardiovascular Science,
University of Liverpool & Liverpool Heart and Chest Hospital,
Liverpool, UK
And
Aalborg Thrombosis Research Unit,
Department of Clinical Medicine, Aalborg University,
Aalborg, Denmark

Peck Lin Lip
Consultant Ophthalmologist (Medical Retina Specialist)
Honorary Senior Lecturer, University of Birmingham
Birmingham & Midland Eye Centre
Sandwell & West Birmingham NHS Hospitals Trust
Birmingham UK

Stefanie Lip
Specialist registrar in Clinical Pharmacology & Therapeutics and General Internal Medicine
Queen Elizabeth University Hospital
Glasgow, UK

Sheon Mary
Institute of Cardiovascular & Medical Sciences
BHF Glasgow Cardiovascular Research Centre
University of Glasgow
Glasgow, UK

Sunil K. Nadar
Senior consultant Cardiologist
Department of Medicine
Sultan Qaboos University Hospital
Muscat, Oman

Sandosh Padmanabhan
Professor of Cardiovascular Genomics and Therapeutics,
Institute of Cardiovascular and Medical Sciences,
University of Glasgow
Glasgow, UK

Giacomo Rossitto
Institute of Cardiovascular & Medical Sciences
BHF Glasgow Cardiovascular Research Centre
University of Glasgow
Glasgow, UK
And
Dipartimento di Medicina,
DIMED, Università degli Studi di Padova,
Padova, Italy

Thomas Salmon
Liverpool University Hospital Foundation trust
Liverpool, UK

Rajiv Sankaranarayanan
Heart Failure Clinical Lead (Aintree University Hospital and Community) Consultant Cardiologist
NIHR Research Scholar and Honorary Clinical Lecturer (University of Liverpool)
Liverpool Centre for Cardiovascular Science
Liverpool University Hospitals NHS Foundation Trust
Liverpool, UK

James Sheppard
University Research Lecturer
Wellcome Trust/Royal Society Sir Henry Dale Fellow
Nuffield Department of Primary Care Health Sciences
University of Oxford
Radcliffe Primary Care
Radcliffe Observatory Quarter
Oxford, UK

Gurbhej Singh
Assistant Professor of Cardiology,
Dayanand Medical College and Hospital (Unit Hero DMC heart institute),
Ludhiana, India

Gurpreet Singh Wander
Professor and Head of Cardiology,
Dayanand Medical College and Hospital (Unit Hero DMC heart institute),
Ludhiana, India

Jan A. Staessen
Studies Coordinating Centre,
Research Unit Hypertension and Cardiovascular Epidemiology,
KU Leuven Department of Cardiovascular Diseases,
University of Leuven,
Campus Sint Rafaël,
Kapucijnenvoer
Leuven, Belgium.
And
Research Institute Alliance for the Promotion of Preventive Medicine,
Mechelen, Belgium.

Michael Stowasser
Director, Hypertension Unit, Princess Alexandra Hospital,
Director, Endocrine Hypertension Research Centre
University of Queensland Diamantina Institute
Brisbane, Australia

Martin Wolley
Consultant Nephrologist
Department of Renal Medicine, Royal Brisbane and Women's hospital
Hypertension unit, Princess Alexandra Hospital
The University of Queensland
Brisbane, Australia

Gregory Y. H. Lip
Professor of Cardiovascular medicine
University of Liverpool,
Liverpool, UK
And
Visiting Professor
Aston University
Birmingham UK

Harsh Goel
Department of Medicine,
St Luke's University Hospital,
Bethlehem, PA, USA
And
Associate Professor of Medicine,
Lewis Katz School of Medicine,
Temple University,
Philadelphia, PA, USA

Iffy R. Mordi
Clinical Senior Lecturer and Consultant Cardiologist
University of Dundee and Ninewells Hospital and Medical School,
Dundee, UK

Chim Lang
Head, Division of Molecular & Clinical Medicine
School of Medicine, University of Dundee
Dundee, UK
And
Editor-in-Chief Cardiovascular Therapeutics,
Chairman - Heart Failure Working Group, Managed Clinical Network for CHD

Shankar Patil
Specialist Registrar
Leeds teaching hospitals NHS trust
Leeds UK

Muzahir Tayebjee
Consultant Cardiologist
Leeds teaching Hospitals NHS trust
Leeds UK

Gloria Valdes
Professor Emeritus
Departamento de Nefrología
Facultad de Medicina
Pontificia Universidad Católica
Santiago, Chile

Alena Shantsila
Liverpool Centre for Cardiovascular Science,
University of Liverpool,
Liverpool, UK

Fang-Fei Wei
Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium.
And
Department of Cardiology,
the First Affiliated Hospital of Sun Yat-Sen University,
Guangzhou, Guangdong, China

Chen Liu
Department of Cardiology,
the First Affiliated Hospital of Sun Yat-Sen University,
Guangzhou, Guangdong, China

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