Human Reproductive and Prenatal Genetics

Human Reproductive and Prenatal Genetics
Preț: 937,65 lei
987,00 lei (-5%)
Disponibilitate: la comandă (vezi secțiunea "Despre livrare")
ISBN: 9780128135709
Anul publicării: 2018
Pagini: 710


Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available.

  • Features chapter contributions from leading international scientists and clinicians
  • Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more
  • Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics based approaches

Part I. Reproductive Tract Development and Gametogenesis
1. Developmental Genetics of the Male Reproductive System
2. Genetics and genomics of early gonad development
3. Genetics of Meiotic Chromosome Dynamics and Fertility
4. Effects of Aging on Sperm Chromatin
5. In Vitro Spermatogenesis from Pluripotent Stem Cells
6. Developmental Genetics of the Female Reproductive Tract
7. The Molecular Genetics of Oogenesis
8. Epigenetic Control of Oocyte Development
9. RNA Binding Protein Networks and Translational Regulation in Oocytes
10. Translational Regulation of Gene Expression during Oogenesis and Pre-implantation Embryo Development
11. MicroRNAs in Gametes and Preimplantation Embryos: Clinical Implications

Part II. Embryo Implantation, Placenta Development and Pregnancy
12. Transcriptomics of the Human Endometrium and Embryo Implantation
13. Epigenetic Modifications in the Human Placenta
14. microRNAs in pregnancy: implications for basic research and clinical management
15. Genetics and Genomics of Preterm Birth
16. The Intergenerational Effects on Fetal Programming

Part III. Infertility and Assisted Reproductive Technology
17. Genetic Testing in Male Infertility
18. Genetics and Genomics of Endometriosis
19. Genetics and Genomics of Primary Ovarian Insufficiency
20. Genetics of Polycystic Ovary Syndrome
21. Genetics and Genomics of Recurrent Pregnancy Loss
22. Human Genetics and Assisted Reproduction in Endometriosis
23. Uterine Transplantation

Part IV. Preimplantation/Prenatal Genetic Diagnosis and Screening
24. Epidemiology and Genetics of Human Aneuploidy
25. Next Generation Sequencing for Gene Panels and Clinical Exomes
26. Chromosomal Microarrays and Exome Sequencing for Diagnosis of Fetal Abnormalities
27. Noninvasive Prenatal Testing for Genetic Diseases
28. Non-Invasive Prenatal Testing by Cell-Free DNA: Technology, Biology, Clinical Utility and Limitations
29. Prenatal diagnosis and treatment of genetic steroid disorders
30. Application of Gene-Editing Technologies in Embryos and Their Potential for Gene Therapy

Edited by Peter C. K. Leung, Professor, Department of Obstetrics and Gynecology, University of British Columbia, Canada and Jie Qiao, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing University Third Hospital, Haidian District, Beijing, China.


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