Sperm Cell: Production, Maturation, Fertilization, Regeneration

This is a comprehensive and definitive account of the human male gamete. The volume summarizes many unique and revealing characteristics of the sperm cell that have only recently been identified. It provides a detailed overview of human sperm production, maturation and function, and looks at how these processes affect and influence fertility, infertility and ART. This is the first dedicated account of the sperm cell to be published in almost a decade. The volume thus provides a very timely review of the most recent research and developments, augmented with the latest references. This book will appeal to all practitioners and scientists in reproductive medicine and in particular to clinical scientists, graduate and post-graduate scientists, and laboratory personnel.

• Written by leading international authorities in the field • First comprehensive coverage of the sperm cell for over eight years

Contents
1. Anatomical and compartmental analysis Peter Sutovsky and Gaurishankar Manandhar; 2. Sperm chromatin stability and susceptibility to damage in relation to its structure Jeffrey A. Shaman and W. Steven Ward; 3. Genomic and proteomic approaches to defining sperm production and function Sarah Conner, Linda Lefièvre and Christopher L. R. Barratt; 4. The epididymis and sperm maturation Trevor Cooper and C. H. Yeung; 5. Control of motility Claude Gagnon and Eve de Lamirande; 6. Regulation of capacitation Pablo Visconti and B. M. Gadella, 7. ROS's: friend or foe John Aitken and Liga Bennetts; 8. Testing sperm manufacturing quality: the sperm-zona binding assay Sergio Oehninger and Daniel Franken; 9. Genetics: a basic science perspective Peter Vogt; 10. Sex chromosome abnormalities and male infertility: a clinical perspective Shai Shefi and Paul J. Turek; 11. Epigenetic patterning in male germ cells: importance of DNA methylation to progeny outcome Jacquetta Trasler and Sophie La Salle; 12. The DAZ gene family and human germ cell development from embryonic stem cells Mark S. Fox, Renee A. Reijo Pera and Amander T. Clark; Index.

Prize Winner
BMA Book Awards 2007 - Highly commended

Contributors
Peter Sutovsky, Gaurishankar Manandhar, Jeffrey A. Shaman, W. Steven Ward, Sarah Conner, Linda Lefièvre, Christopher L. R. Barratt, Trevor Cooper, C. H. Yeung, Claude Gagnon, Eve de Lamirande, Pablo Visconti, B. M. Gadella, John Aitken, Liga Bennetts, Sergio Oehninger, Daniel Franken, Peter Vogt, Shai Shefi, Paul J. Turek, Jacquetta Trasler, Sophie La Salle, Mark S. Fox, Renee A. Reijo Pera, Amander T. Clark.