Manual of Pediatric Hematology and Oncology

This will be the fifth edition of successful clinical manual aimed at all practitioners treating children with cancer and blood diseases, such as leukemia, anemia, and bone marrow failure. As with previous editions, this edition will be a comprehensive book on patient management, replete with algorithms and flow diagrams on diagnosis and management. Its concise and easy-to-read format will enable readers to make accurate diagnoses and permit them to treat patients even if they have not had extensive previous hematologic or oncologic experience. It will contain a list of normal values at various ages in children, which is extremely useful as a reference in the management of patients.


Since the previous edition was written five years ago, there have been considerable advances particularly in the treatment and management of oncologic diseases in children. These oncology sections (approximately 40% of the book) will be entirely rewritten to incorporate all current protocols. In addition, advances in many other areas will require that all hematology sections of the book be updated.


The successful basic format and content of clinical manifestations, diagnosis and differential diagnosis will be maintained – as in previous editions, the editor will closely edit chapter content to maintain consistency in format, depth, and style. In addition to the core group of hematologists and oncologists from Schneider Children’s Hospital, who contributed to the 4th edition, the editor is inviting 15 new authors who are all experts from around the country – in order to keep up with the advances in management of hem/onc diseases. The book will reflect the 45+ years of practical experience by the editor as well as the extensive clinical experience and research expertise of the various contributors.




Readership
Medical students, pediatric residents, pediatric fellows in hematology/oncology, practicing hematologists and oncologists pediatric oncology nurses, nurse practitioners and physician assistants

Quotes

PRAISE FOR THE FOURTH EDITION:

"This text is a very good intermediate level book focusing on the clinical presentation, diagnosis, and management of both hematologic and oncologic disorders observed in children. The combination of text, tables, and outlined material makes the information easy to access. It provides a handy text for pediatricians caring for both hematologic and oncologic problems. It also is particularly suitable for pediatric students and residents. The comprehensive tables of normal values in infants and children at the end of the text are very useful."
- Marshall Lichtman, URMC, Rochester (2005)



PRAISE for the FIFTH EDITION:

"This Manual is an amazing amalgam of an extremely practical workbook and also more than a bird's eye-view of the entire scope of pediatric hematology-oncology. In my opinion, this Manual is a "must-have" book for three distinct and important potential users: clinicians in practice, residents and fellows in training, and medical students. Dr. Philip Lanzkowsky deserves congratulations for this authoritative and yet highly accessible text."

-Kanti R. Rai, MD, Chief, Division of Hematology-Oncology, Long Island Jewish Medical Center, Professor of Medicine, Albert Einstein College of Medicine, New York, USA

"The Fifth Edition of the Manual of Pediatric Hematology and Oncology constitutes an evolutionary leap from previous editions. In addition to an instructive manual containing the body of information required as background for the numerous informative and clearly organized tables, algorithms and instructions, the present extensive and thoughtfully produced book is also a source of scientific and clinical learning on the broad spectrum of subjects that make up pediatric hematology and oncology - in this era of rapid, and often bewildering, developments.

The style is clear and authoritative, attesting to what the editor's colleagues and disciples call "the Lanzkowsky way of teaching." The contributors are internationally known experts in their various subjects, and the material is admirably up to date. This edition is of great value not only to pediatric teams of hematologists and oncologists, but also to pediatric practitioners in general."

-Moshe Berant, MD, Professor (Emeritus) of Pediatrics, Rambam Health Care Campus and Technion-Faculty of Medicine, Israel

"I would not be without this book and have been recommending it to postgraduate students in paediatrics and paediatric haematology and oncology for a number of years. It is packed with up-to-date, concise and practical information. The detailed tables and algorithms are extremely useful both as teaching and management tools.

I was particularly impressed with the expanded information on haemaglobinopathies and haematologic manifestations of infectious diseases in this 5th edition. This book should be on the shelves of all paediatricians and paediatric haematologists."

-Prof. Patricia Hartley, MD, Emeritus Head of Paediatric Haematology and Oncology, School of Child and Adolescent Health, University of Cape Town, South Africa


Contents
Table of Contents

Chapter 1

Classification & Diagnosis of Anemia during Childhood

Philip Lanzkowsky

Chapter 2

Anemia During the Neonatal Period

Philip Lanzkowsky

Chapter 3

Iron-Deficiency Anemia

Philip Lanzkowsky

Chapter 4

Magaloblastic Anemia

Philip Lanzkowsky

Chapter 5

Hematologic Manifestations of System Illness

Lawrence Wolfe

Chapter 6

Bone Marrow Failure

Jeff Lipton

Chapter 7

Hemolytic Anemia due to Membrane & Enzyme Defects

Lawrence Wolfe

Chapter 8

Hemoglobinopathies…. Sickle Cell Disease/ Thalassemia

Janet Kwiatkowski

Chapter 9

Extracorpuscular Hemolytic Disease

Lawrence Wolfe

Chapter 10

Polycythemia

Josef Thomas Prchal

Chapter 11

Disorders of the White Blood Cells

Jill S. Menell

Chapter 12

Disorders of Platelets

James B. Bussel

Chapter 13

Hemostatic Disorders

Suchritra Acharya

Chapter 14

Thrombotic Disorders

Suchritra Acharya

Chapter 15

Lymphadenopathy and Splenomegaly

Philip Lanzkowsky

Chapter 16

Lymphoproliferative Disorders, Myelodysplastic Syndromes, Myeloprof Dis

David T. Teachey

Chapter 17

Leukemias

Arlene Redner

Chapter 18

Histiocytosis Syndromes

Robert J. Arceci

Chapter 19

Hodgkin's Disease

Debra L. Friedman

Chapter 20

Non-Hodgkin Lymphoma

Mitchell Cairo

Chapter 21

Central Nervous System Malignancies

Mark Atlas

Chapter 22

Neuroblastoma

Julie R. Park

Chapter 23

Wilms' Tumor

Jeffrey Stuart Dome

Chapter 24

Rhabdomyosarcoma&Other Soft Tissue Sarcomas

Carolyn Fein-Levy

Chapter 25

Malignant Bone Tumors

Neyssa Marina

Chapter 26

Retinoblastoma

Debra L. Friedman

Chapter 27

Germ Cell Tumors

Thomas Olson

Chapter 28

Primary Hepatic Tumors

Thomas Olson

Chapter 29

Hematopoietic Stem Cell Transplantation

IndiraSahdev

Chapter 30

Management of Oncologic Emergencies

Susan R. Rheingold

Chapter 31

Supportive Care of Patients with Cancer

Lawrence Wolfe

Chapter 32

Eval, Investigations & Management of Late Effects of Childhood Cancer

Jonathan Fish

Chapter 33

Psycho-Social Aspects of Managing Oncologic Patients

Lori S. Wiener




Author Information
Edited by Philip Lanzkowsky, Schneider Children's Hospital, New Hyde Park, New York, U.S.A.