Intestinal Polyps and Polyposis: From Genetics to Treatment and Follow-Up

Nowadays, we are dealing more frequently with the entity of large intestine polyps, as endoscopy and bowel cancer screening programmes are rapidly expanding. Often a single polyp is involved, but more complex situations are also encountered, including the well-defined pattern of polyposis. These situations can fall into a gray area, not only for diagnosis, but also for the correct treatment and follow-up. New developments in pathophysiology and treatment options are leading to new questions. This handbook aims to offer a integrated approach for all physicians (doctors) who deal with these issues, by presenting up-to-date discussion from genetics through treatment, to implications of genetic counseling. It will also help specialists to offer more "evidence-based" treatments, by implementing the best clinical individual judgement informed by the best current scientific evidence.


Table of contents
1 The Impact of Bowel Cancer Screening: Are We Going to Observe a Different Disease?- 2 Pathological Features of Sporadic Colonic Adenoma.- 3 Serrated Neoplasia Pathway.- 4 Genetic and Clinical Features of Familial Adenomatous Polyposis (FAP) and Attenuated FAP.- 5 Not Only FAP. Other Rare Polyposis Syndromes.- 6 Diet, Polyps, and Cancer: Where is the Truth?.- 7 Chemoprevention of Colonic Cancer. Is There a Foreseeable Future?.- 8 The Role of Imaging in Colonic Polyps and Polyposis.- 9 Rectal Polyps and Early Rectal Cancer. Assessment by Three-Dimensional.- Endorectal Ultrasonography.- 10 What is What? Clinical Vignettes of Multiple Polyps.- 11 Diagnosis and treatment of upper GI polyps in polyposis.- 12 Lower Gastrointestinal Endoscopy for Polyps and Polyposis.- 13 Management and Treatment of Complications in Diagnostic and Therapeutic Lower Gastrointestinal Tract Endoscopy.- 14 Follow-up After Endoscopic Polypectomy.- 15 Surgical Options for FAP.- 16 Restorative Proctocolectomy with Ileal Pouch-Anal Anastomosis for Familial Adenomatous Polyposis. The Role of Laparoscopy - An Overview.- 17 Rectal Polyps after Ileorectal Anastomosis. What is the Future.- 18 Anorectal Polyps and Polypoid Lesions.- 19 Polypectomy of Anorectal Polyps and Polypoid Lesions. Why, When, and How?.- 20 Quality of Life and FAP Patients.- 21 Psychological and Medico-legal Aspects of Genetic Counseling in Familial Adenomatous Polyposis.- 22 The Role of a Registry in Familial Adenomatous Polyposis (FAP).- 23 Coping With FAP. The Role Of Patients' Associations. Subject Index.