Hematology, Clinical Principles and Applications

This comprehensive text examines normal hematopoiesis through diseases of erythroid, myeloid, lymphoid and megakaryocytic origins. Hemostasis and coagulation theory, testing, and instrumentation are also thoroughly discussed. Beautiful full-color illustrations throughout the text enhance comprehension and allow students to realistically visualize hematology concepts.




Features


Detailed, full-color illustrations appear near hematology concept discussions to visually support comprehension and recognition.
Opening Case Studies present real-life scenarios to apply concepts presented in each chapter.
Learning Objectives and Review Questions work together to list expected outcomes and then test those concepts for each chapter.
A Bulleted Summary highlights the key concepts at the end of each chapter.
Hematology/Hemostasis Reference Ranges inside the front and back covers provide quick reference.





What's New


Three new chapters detail significant information: An Overview of Clinical Laboratory Hematology, Hematology in Selected Populations, and Monitoring Anticoagulant Therapy.
All chapters have been revised to feature the most current technology and research updates.
The included Glossary of Terms and consistent pedagogy ensure a cohesive, effective tool for learning.
Two well-respected editors contributed more significantly to this third edition: George Fritsma shared his expertise for the Hemostasis section and Kathy Doig managed the pedagogical features.





Contents
Introduction to Hematology
1. An Overview of Clinical Laboratory Hematology NEW!
2. Safety in the Hematology Laboratory
3. Specimen Collection
4. Care and Use of the Microscope
5. Quality Assurance
Part II: Hematopoiesis
6. Morphology and Function of Cellular Components
7. Hematopoietic Theory
8. Erythrocyte Production and Destruction
9. Metabolism of the Erythrocyte
10. Hemoglobin Metabolism
11. Iron Metabolism
12. Leukopoiesis
13. Platelet Production, Structure, and Function
Part III: Routine Laboratory Evaluation of Blood Cells
14. Routine Testing in Hematology
15. Examination of the Peripheral Blood Smear and Correlation with the Complete Blood Count
16. Bone Marrow Overview
Part IV: Body Fluid Examination
17. Body Fluids in the Hematology Laboratory
Part V: Erythrocyte Disorders
18. Anemias: RBC Morphology and Approach to Diagnosis
19. Disorders of Iron and Heme Metabolism
20. Anemias Caused by Defects of DNA Metabolism
21. Bone Marrow Failure
22. Introduction to Increased Destruction of Erythrocytes
23. Intracorpuscular Defects Leading to Increased Erythrocyte Destruction
24. Extracorpuscular Defects leading to Increased Erythrocyte Destruction--Nonimmune Causes
25. Extracorpuscular Defects leading to Increased Erythrocyte Destruction--Immune Causes
26. Hemoglobinopathies (Structural Defects in Hemoglobin)
27. Thalassemias
Part VI: Leukocyte Disorders
28. Morphologic and Distributive Leukocyte Disorders
29. Introduction to Leukocyte Neoplasms
30. Cytochemistry
31. Cytogenetics
32. Molecular Diagnostics in the Clinical Laboratory
33. Flow Cytometric Analysis in Hematologic Disorders
34. Myeloproliferative Disorders
35. Myelodysplastic Syndromes
36. Acute Leukemias
37. Mature Lymphoid Neoplasms
Part VII: Hematology in Selected Populations
38. Hematology in Selected Populations NEW!
Part VIII: Cell Counting Automation
39. Cell Counting Automation
Part IX: Hemostasis and Thrombosis
40. Normal Hemostasis and Coagulation
41. Hemorrhagic Coagulation Disorders
42. Thrombosis Risk Testing
43. Thrombocytopenia and Thrombocytosis
44. Qualitative Disorders of Platelets
45. Evaluation of Hemostasis
46. Monitoring Anticoagulant Therapy NEW!
47. Coagulation Instrumentation
Appendix: Answers to Review Questions
Glossary
Index