Heart Transplantation

The only truly comprehensive reference devoted to every aspect of cardiac transplantation not only covers the surgical procedures for donor and recipient but also explores the pre- and post-operative patient management, operative techniques, and non-surgical cardiac management options. Its coverage encompasses everything from historical and scientific foundations of transplantation through the cardiac conditions which lead to transplantation to the procedure and its possible results.

Key Features

Covers the critical subjects of basic science, causation theories, clinical manifestation, and available therapies for acute and chronic allograft rejection.

Devotes an entire chapter to pediatric heart transplantation and details those areas which are unique to the infant, child, and adolescent.

Provides a thorough explanation of the immunologic basis of transplantation.

Dedicates a chapter to techniques of analysis in outcomes research in both single and multi-institutional studies.

Describes individual post-transplantation infections along with treatment options and doses.

Offers detailed survival analyses with risk factors for various causes of death based on the most current data available.

Includes information on all currently used immunosuppresive drugs and other modalities in helpful tables which includes data on mechanism, chemistry, metabolism, indications, and toxicities of each agent.

Facilitates quick reference with extensive outlines and bolded phrases.

Related Titles

Sabiston & Spencer Surgery of the Chest, 7th Edition : 2-Volume Set

Table of Contents
Background of Heart Transplantation
1. History of Cardiac Transplantation
2. Immunology in Relation to Cardiac Transplantation
3. Methodology for Clinical Research in Cardiac Transplantation

The Patient Before Transplantation
4. Pathophysiology and Clinical Features of Heart Failure
5. Medical and Nontransplant Surgical Therapy of Heart Failure

6. Recipient Evaluation and Selection
7. Pretransplant Immunologic Evaluation and Management
8. Mechanical Support of the Failing Heart

The Transplanted Heart
9. The Donor Heart
10. The Heart Transplant Operation
11. Physiology of the Transplanted Heart

Management of the Transplant Patient
12. Management of the Recipient During the Transplant Hospitalization
13. Immunosuppressive Modalities
14. Cardiac Allograft Rejection
15. Infections After Heart (and Heart/Lung) Transplantation

Long-Term Outcome After Heart Transplantation
16. Survival After Heart Transplantation
17. Cardiac Allograft Vasculopathy (Chronic Rejection)
18. Other Long-Term Complications
19. Quality of Life After Heart Transplantation

Special Situations in Heart Transplantation
20. Pediatric Heart Transplantation
21. Combined Heart and Other Organ Transplantation
22. Cardiac Retransplantation
23. Xenotransplantation
24. Resource Allocation in Heart Transplantation



Author Information
By James K. Kirklin, MD, Professor of Surgery, Director of Cardiothoracic Transplantation, UAB Endowed Professor of Cardiovascular Surgical Research, Division of Cardiothoracic Surgery, University of Alabama at Birmingham Medical Center, Birmingham, AL; James B. Young, MD, Medical Director, Kauffman Center for Heart Failure, Head, Section of Heart Failure and Cardiac Transplant Medicine, Department of Cardiology , Cleveland Clinic Foundation, Cleveland, OH; and David C. McGiffin, MD, Professor Surgery, Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham Medical Center, Birmingham, AL