Esophageal Cancer: Principles and Practice

Gastroesophageal cancers are the most common form of cancer incidents, and the second most common cause of death among cancer patients. In 2000, it was estimated that over one million new cases of gastroesophageal cancers were diagnosed worldwide, and over 900,000 individuals died from the disease.
Using a multi-disciplinary approach, Esophageal Cancer: Principles and Practice addresses the complexities encountered in the understanding and management of esophageal cancers. Written by the world's leading experts in surgery, medical oncology, radiation oncology, gastroenterology, pathology, radiology, nutrition, nurse specialists, palliative medicine, and research relating to neoplasia of the esophagus, this text will serve as the definitive resource and enable practitioners to provide the best possible patient care. Presented in an accessible and useful format, this text is a valuable reference to all practitioners participating in the care of this high-needs population.

Special Features Include:

Complete coverage of the two most common tumors: squamous cell carcinoma and adenocarcinoma
In-depth coverage of uncommon tumors
In-depth coverage of each topic with equal emphasis applied to both technical and multidisciplinary aspects of treatment
In-depth treatment of non-surgical topics in management at different phases of the disease
Wide-ranging attention to the disease's biologic aspects and basic science, contributing greatly to palliative care
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Reviews
"In summary, Esophageal Cancer: Principles and Practice is an important addition to the oncology literature. It offers valuable information to readers at all stages of their professional careers- from the young new GI oncologist to the seasoned expert. it is truly a well-written, practical, comprehensive text. It should serve as a helpful, handy reference to anyone involved in the treatment of this disease."-Gastrointestinal Cancer Research, January/February 2011, Volume 4, Issue 1
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Contents
Section: I BIOLOGY; 1. Esophageal Embryology and Congenital Disorders 2. Esophageal Anatomy; 3. The Biology of Epithelial Esophageal Cancer; 4. The Biology of Mesenchymal Esophageal Tumors; 5. Barrett's Esophagus: Epidemiology and Pathogenesis; 6. Barrett's Esophagus: Molecular Biology; 7. Barrett's Esophagus: Preclinical Models for Investigation; 8. Barrett's Esophagus: Screening and Surveillance; 9. Barrett's Esophagus: Models for Cost-Effective Screening and Surveillance; 10. Barrett's Esophagus: Chemoprevention; 11. Epidemiology of Esophageal Cancer: Molecular; 12. Epidemiology and Risk of Esophageal Cancer: Clinical; 13. Pathology of Barrett's Esophagus and Esophageal Neoplasms; 14. The Link Between Esophageal Cancer and Morbid Obesity; 15. The Relationship Between ,Helicobacter Pylori and Barrett's Esophagus; 16. Ethnic Disparities in Cancer of the Esophagus; Section II: IMAGING AND STAGING 17. State of the Art in Esophageal Imaging: Endoscopic Technology and Evaluation of Esophageal Mucosa; 18. Esophageal Imaging: Anatomic; 19. Esophageal Imaging: Functional - PET; 20. Esophageal Imaging: Functional - MRI; 21. Esophageal Cancer Staging -Clinical; 22. Esophageal Cancer Staging - EMR; 23. Esophageal Cancer Staging - Surgical; 24. Restaging after Neoadjuvant Therapy; 25. Revisions in the Staging System for Esophageal Cancer; Section III: PRINCIPLES OF THERAPY; 26. Rationale for Tailored Treatment; 27. Principles of Multimodality Therapy; 28. Principles of Chemotherapy; 29. Principles of Systemic Therapy: Targeted Therapy; 30. Principles of Radiation Therapy; 31. Principles of Surgical Therapy; 32. The Relationship Between Volume and Outcome in the Treatment of Esophageal Cancer; Section IV: TUMOR TYPES; 33. Benign: Lipoma; 34. Benign: Fibrovascular Polyp; 35. Benign: Fibrolipoma; 36. Benign: Hemangioma; 37. Benign: Granular Cell Tumors; 38. Benign: Neurofibroma; 39. Benign: Leiomyoma; 40. Benign: Hamartoma; 41. Benign: Congenital - Duplication Cysts; 42. Benign: Congenital - Bronchogenic Cysts; 43. Malignant: Squamous Cell Carcinoma and Variants; 44. Malignant: Esophageal Adenocarcinoma and Variants; 45. Malignant: Esophageal Adenocarcinoma of the Cardia and Proximal Stomach; 46. Malignant: Mesenchymal Tumors; 47. Malignant: Lymphoma; 48. Malignant: Metastatic; Section V: THERAPY49. Multidisciplinary Care Team: Structure and Format; 50. Informed Consent in the Esophageal Cancer Patient; 51. Review and Synthesis of Clinical Trials in Esophageal Cancer; 52. Pretreatment Planning in Radiation Therapy of the Esophagus; 53. Adjuvant (Postoperative) Therapy; 54. Neoadjuvant Therapy; 55. Definitive Radiochemotherapy; 56. Endoscopic Therapies for Barrett's Esophagus; 57. Endoscopic Therapy for Superficial Cancerr; 58. Therapy for Advanced Locoregional Cancer; 59. Treatment Options for Locally Recurrent Esophageal Cancer; 60. Preoperative Immunonutrition; 61. Surgery Techniques: Management of Benign Esophageal Tumors; 62. Surgery Techniques: Patient Preparation and Surgical Approach in Cancer Treatment; 63. Surgery Techniques: Anesthesia in the Esophageal Cancer Patient; 64. Surgery Techniques: Anastomotic Technique and Selection of Location; 65. Surgery Techniques: Conduit Preparation and Route of Reconstruction; 66. Surgery Techniques: Vagal-Sparing Esophagectomy; 67. Surgery Techniques: Minimally Invasive Esophagectomy; 68. Surgery Techniques: Ivor-Lewis Esophagectomy; 69. Surgery Techniques: Transhiatal Esophagectomy without Thoracotomy; 70. Surgery Techniques: Three-Field Esophagectomy; 71. Surgery Techniques: En Bloc Esophagectomy; 72. Surgery Techniques: Left Transthoracic and Thoracoabdominal Esophagectomy; 73. Surgery Techniques: Resection of Cancer Involving the Cervicothoracic Esophagus; 74. Surgery Techniques: Transhiatally Extended Total Gastrectomy; 75. Surgery Techniques: Salvage Esophagectomy; 76. Surgery Techniques: Postoperative Care; 77. Managing the Complications of Multimodality Therapy; 78. Postoperative Care and Management of the Complications of Surgical Therapy; 79. Quality of Life after Esophagectomy; 80. Proper Follow-up after Definitive Therapy; Section VI: PALLIATION; 81. Guidelines for Palliative Care: Hospital and Hospice; 82. Care of the Psychosocial Needs of the Patient and Family; 83. Objective Scoring Systems in the Palliative Setting; 84. Guidelines for Pain Control in the Esophageal Cancer Patient; 85. Endoscopic Palliation of Dysphagia: Photodynamic Therapy; 86. Endoscopic Palliation of Dysphagia: Stenting; 87. Endoscopic Palliation of Dysphagia: Laser; 88. Endoscopic Palliation of Dysphagia: Brachytherapy; 89. Surgical Palliation: Current Role; 90. Perforated Esophageal Cancer; 91. Radiation; Section VII: FUTURE DIRECTIONS; 2. Molecular Outcome Prediction; Index
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About the Authors
Blair Jobe, MD
Blair A. Jobe, MD is Sampson Family Endowed Associate Professor of Surgery, Division of Thoracic and Foregut Surgery, The Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.

Thomas Charles, MD

Charles R. Thomas, Jr., MD, Professor and Chairman of the Department of Radiation Medicine, Professor of Hematology/Oncology, Knight Cancer Institute, Oregon Health Sciences University

John Hunter, MD

John G. Hunter, MD is Mackenzie Professor and Chairman of the Department of Surgery, Oregon Health Sciences University.