DeVita, Hellman, and Rosenberg's Cancer Principles & Practice of Oncology: Two-Volume Set Plus Integrated Content Website

Acclaimed by the worldwide medical community as "a staple reference text in the medical oncologist's library" (JAMA), DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology is now in its Eighth Edition. This edition is in full color for the first time, has a new editor, Theodore S. Lawrence, MD, PhD, a radiation oncologist, and has two Associate Scientific Advisors, Ronald A. DePinho, MD and Robert A. Weinberg, PhD, with special expertise in molecular biology. More than 40 chapters are entirely new, and more than 70 have been rewritten by new contributing authors. Plus, this edition has an exciting new companion Website.

The text provides cutting-edge, practical information on the science of oncology and the multimodality treatment of every cancer type. To ensure a balanced, multidisciplinary approach, each major treatment chapter is co-authored by a surgeon, a medical oncologist, and a radiation oncologist. Treatment of each cancer type is discussed by stage, with coordinated guidelines on the role of each treatment modality at each stage. Each major treatment section is preceded by an updated brief chapter describing the molecular biology of the cancer and the implications of molecular biology for patient management. Full consideration is also given to cancer prevention, screening, palliative care, supportive oncology, and quality of life issues.

A companion Website offers the fully searchable online text, an image bank, links to journal articles, and a question bank.

Table Of Contents
Contributing Authors

Preface

Acknowledgments

VOLUME ONE

PART 1: Molecular Biology of Cancer
1 Cancer: A Conceptual Framework
2 Genomics and Proteomics
3 Destabilization of the Cancer Genome
4 Telomeres, Telomerase, and Cell Immortalization
5 Cell Signaling
6 Cell Cycle
7 Programmed Cell Death
Immortalization
8 Angiogenesis
9 Invasion and Metastasis
10 Cancer Stem Cells

PART 2: Principles of Oncology

11 Etiology of Cancer: Tobacco
12 Etiology of Cancer: Cancer Susceptibility Syndromes
13 Etiology of Cancer: Viruses
Section 1 RNA Viruses
Section 2 DNA Viruses
14 Etiology of Cancer: Inflammation
Tumor Immune Surveillance
Inflammation and Tumorigenesis
15 Etiology of Cancer: Chemical Factors
DNA Repair Protects the Host from Chemical Carcinogens
Genetic Susceptibility to Chemical Carcinogenesis
16 Etiology of Cancer: Physical Factors
Ultraviolet Light
Asbestos
17 Etiology of Cancer: Dietary Factors
Energy
Alcohol
18 Etiology of Cancer: Obesity and Physical Activity
19 Epidemiology of Cancer
20 Principles of Surgical Oncology
21 Principles of Radiation Oncology
Tumor Oxygenation
22 Principles of Medical Oncology
23 Principles of Immunotherapy
24 Principles of Health Services Research
25 Pharmacology of Cancer Chemotherapy
26 Pharmacology of Cancer Biotherapeutics
27 Pharmacology of Endocrine Manipulation
28 Design and Analysis of Clinical Trials

PART 3: Practice of Oncology

29 Cancer Prevention: Tobacco Dependence and Its Treatment
30 Cancer Prevention: Chemoprevention
31 Cancer Prevention: Role of Surgery in Cancer Prevention
32 Genetic Counseling
33 Cancer Screening
34 Specialized Techniques in Cancer Management
35 Role of Endoscopy in Cancer Management
36 Cancer of the Head and Neck
37 Cancer of the Lung
38 Neoplasms of the Mediastinum
39 Cancers of the Gastrointestinal Tract
40 Cancers of the Genitourinary System
41 Cancer of the Testis

VOLUME TWO

42 Gynecologic Cancers
43 Cancer of the Breast
44 Cancer of the Endocrine System
45 Sarcomas of the Soft Tissue and Bone
46 Benign and Malignant Mesothelioma
47 Cancer of the Skin
48 Melanoma
49 Neoplasms of the Central Nervous System
50 Cancers of Childhood
51 Lymphomas
52 Acute Leukemias
53 Chronic Leukemias
54 Plasma Cell Neoplasms
55 Paraneoplastic Syndromes
56 Cancer of Unknown Primary Site
57 Diagnosis and Treatment of Peritoneal Carcinomatosis
58 Immunosuppression-Related Malignancies
59 Oncologic Emergencies
60 Treatment of Metastatic Cancer
61 Stem Cell Transplantation
62 Infections in the Cancer Patient
63 Management of Adverse Effects of Treatment
64 Supportive Care and Quality of Life
65 Rehabilitation of the Cancer Patient
66 Societal Issues in Oncology
67 Information Systems in Oncology
68 Complementary, Alternative, and Integrative Therapies

PART 4: Newer Approaches in Cancer Treatment

69 Gene Therapy
70 Cancer Immunotherapy
71 Focused Ultrasound
72 RNA Inhibition
73 Charged Particle Therapy
74 Robotic Surgery
75 Nanotechnology

Appendix

Index