Comprehensive Textbook of Genitourinary Oncology

Comprehensive Textbook of Genitourinary Oncology was the first major textbook to focus on the field of genitourinary oncology from the combined perspectives of the molecular biologist, pathologist, oncologist and urologist. The first edition of the book had three fundamental goals: 1) to be a textbook that could be read and used by practicing physicians, 2) to be an authoritative textbook for basic scientists, 3) to be an effective interpretation of this field for trainees in surgery, medical and radiation oncology, and pathology. The goals for the 4th edition remain essentially the same. The book takes a systems approach to this field, with sections on prostate, bladder, kidney, testis, and penile cancers, as well as one each on pediatric and other (less common) malignancies. This volume will introduce and distill the combined knowledge and expertise of specialist from a multitude of scientific and clinical disciplines who are internationally recognized leaders in their fields and who themselves have contributed to the field. As in the last edition, authors will be drawn form the fields of urological surgery, medical oncology, radiation oncology, pathology, radiology as well as translational scientists and epidemiologists.

-NEW! Covers merging image-guided targeted technologies such as magnetic resonance image-guided high-intensity focused ultrasound, which can precisely ablate cancerous cells without damage to surrounding healthy tissue.
--NEW! Greater focus on the multidisciplinary care of patients with urological cancers with improved outcomes dependent on collaborative development of care plans that incorporate evidence-based management.
--NEW! Includes new imaging modalities including diffusion-weighted imaging and magnetic resonance spectroscopic imaging which help clinicians differentiate tumor subtypes and target treatment
--NEW! Increase coverage of molecular classification of cancers and the delineation of critical pathways that can identify new targets for systemic therapy and demonstrate how cells react to particular drugs.
--NEW! Reviews combined imaging technology, such as MR-ultrasound fusion to better guide needle biopsies, and PET-CT imaging to identify and locate biologically active metastatic lesions, as well as novel radiotracers highly specific for key molecules present in
--NEW! Summarize and evaluate the latest research on existing and investigational new drugs.
--Most comprehensive GU cancer book on the market
--Editors represent each of the major sub areas in this field (Vogelzang/medical oncology, Scardino/urology (prostate), Zelefsky/radiation oncology, and Linehan/urology (kidney)
--Multi-modality approach of the book reflects the way in which these cancers are managed and encourages multidisciplinary sales opportunities

Part I: PROSTATE CANCER 1: Epidemiology of Prostate Cancer Edward Giovannucci, Elizabeth A. Platz, and Lorelei Mucci 2: Genetic Basis of Prostate Cancer Stacy Loeb and William B. Isaacs 3: Androgen Receptor Signaling in Castrate Resistant Prostate Cancer Brett S. Carver and Charles L. Sawyers 4: Anatomy and Pathology of Prostate Cancer 4A: Anatomy of the Prostate and the Pathology of Prostate Cancer Peter A. Humphrey 4B: Prostate Cancer: Molecular Pathology and Biologic Determinants Massimo F. Loda 4C: Ets Genes and Prostate Cancer: Implications for Prognosis and Disease Control Jeremy P. Clark and Colin S. Cooper 5: Prevention of Prostate Cancer Barbara Ercole, Javier Hernandez, and Ian M. Thompson, Jr. 6 : Screening and Early Detection 6A: Early Detection of Prostate Cancer with PS Stacy Loeb and William J. Catalona 6B: Screening for Prostate Cancer Freddie C. Hamdy, Jenny L. Donovan, and David E. Neal 7: Prostate Needle Biopsy Techniques and Interpretation Katsuto Shinohara, Viraj A, Thomas Chi, and Peter R. Carroll 8: Staging Systems for Prostate Cancer Alison M. Lake and Sam S. Chang 9: Nomograms for Prostate Cancer Decision-Making Andrew J. Stephenson and Michael W. Kattan 10: Imaging in Prostate Cancer Hedvig Hricak 11: Treatment of Early Stage Prostate Cancer 11A: Quality of Life after Treatment for Early Stage Prostate Cancer Mehrdad Alemozaffar and Martin G. Sanda 11B: Active Surveillance for Prostate Cancer: Rationale, Methods, and Results Laurence Klotz 11C: PLND: Indications for and Technique of Pelvic Lymph Node Dissection Fiona C. Burkhard and Urs E. Studer 11D: Radical Prostatectomy for Clinical Stage T1 and T2 Prostate Cancer James A. Eastham and Peter T. Scardino 11E: Treatment of Early Stage Prostate Cancer: Laparoscopic Radical Prostatectomy Karim Touijer and Bertrand Guillonneau 11F: Robotic-Assisted Laparoscopic Prostectomy Joseph A. Smith, Jr. 11G: Brachytherapy Alone and with External Beam Radiotherapy for Localized Prostate Cancer Michael Zelefsky 11H: Other Interventions for the Treatment of Localized Prostate Cancer (Cryo, Hifu) Stephen Jones and Ryan Berglund 12: Management of High Risk Prostate Cancer 12A: Combined Hormone Therapy and Radiation Therapy for High-Risk Prostate Cancer Michel Bolla and M. Roach 12B: Surgical Management of Clinical T3 (cT3) and Node Positive (pN+) Adenocarcinoma Michael Blute and Jeffrey Karnes 13: Treatment of Locally Recurrent Prostate Cancer 13A: Recurrence Following Radiotherapy: Definitions, Prognosis, and Management Eric M. Horwitz and Gerald E. Hanks 13B: Salvage Radical Prostatectomy for Recurrence Prostate Cancer after Radiation Therapy James A. Eastham 13C: Salvage Brachytherapy for Prostate Cancer Ryan J. Burri and Richard G. Stock 13D: Recurrence Following Radical Prostatectomy: Definitions and Management Lionel L. Ba\u00f1ez, Stephen J. Freedland, and Judd W. Moul 13E: Adjuvant and Salvage Radiotherapy, Post-Prostatectomy Dayssy Alexandra Diaz and Alan Pollack 14: Advanced Prostate Cancer 14A: Biology of Bone Metastases in Men with Prostate Cancer Matthew Smith and Mary Anne Fallon 14B: Initial Management of Metastatic Prostate Cancer Ajjai S. Alva and Maha Hussain 14C: Second Line Treatment: Going Beyond Hormones Howard Scher, Kristofer Prepelica, and Nicholas Mitsiades 14D: Management of Castration-Resistant Prostate Cancer Sonia M. Seng, Mari Nakabayashi, and William K. Oh Part II: BLADDER CANCER AND UPPER TRACT CANCER 15: The Epidemiology of Bladder Cancer Jian-Min Yuan and Heather H. Nelson 16: Cytology and Pathology of Carcinomas of the Urinary Tract Victor Reuter, Hikmat Al-Ahmadie, and Oscar Lin 17: Molecular Biology and Prognostic Markers in Bladder Cancer Anirban P. Mitra, Dan Theodorescu, Seth P. Lerner, Richard J. Cote, and Ram H. Datar 18: Screening, Early Detection, and Prevention of Bladder Cancer Antonio J Otero, H. Barton Grossman, and Colin P.N. Dinney 19: Bladder Cancer Staging Theresa M. Koppie and Bernard H. Bochner 20: Imaging of Transitional Cell Carcinoma Mukesh G. Harisinghani and Efr\u00e9n J. Flores 21: Upper Tract Tumors 21A: Management of Upper Tract Tumors Guilherme Godoy and Seth P. Lerner 21B: Minimally-Invasive Surgical Procedures (Robotic, Laparoscopic, Single-Site) for Treatment of Upper Tract Tumors David A. Duchene and Howard N. Winfield 22: Non Muscle Invasive Bladder Cancer 22A: Low Risk Non-Invasive Bladder Cancer J. Alfred Witjes 22B: High Risk Non-Muscle Invasive Bladder Cancer: Ta High Grade and Carcinoma In-Situ Andrew J. Lightfoot, Henry M. Rosevear, and Michael A. OÆDonnell 22C: Lamina Propria Invasive Bladder Cancer (T1) Guido Dalbagni 23: Invasive Bladder Cancer 23A: Radical Cystectomy & Pelvic Lymph Node Dissection Bochner, Quek, Skinner 23B: Role of Radical Cystectomy in Patients with Advanced Bladder Cancer S. Machele Donat and Harry W. Herr 23C: Management of Complications and Long Term Follow-up Cheryl Lee 24: Bladder Preservation Strategies for Invasive Bladder Cancer 24A: Trimodality Therapy: Selective Bladder Preservation in the Treatment of Muscle-invasive Bladder Cancer Mohamed E. Abazeed, Jason A. Efstathiou, Niall M. Heney, Andrzej Niemierko, Donald S. Kaufman, and William U. Shipley 24B: Radical Transurethral Resection of the Bladder and Partial Cystectomy for Invasive Bladder Cancer Eduardo Solsona 25: Urinary Diversions and Reconstructions 25A: Cutaneous Urinary Diversions G. Joel DeCastro, Michael C. Large, and Gary D. Steinberg 25B: Orthotopic Bladder Substitution Richard Hautmann:, Urs Studer, Robert Mills, and William Turner 26: Neo Adjuvant and Adjuvant Chemotherapy in Muscle Invasive Bladder Cancer Cora N. Sternberg 27: Chemotherapy for Metastatic Bladder, Alone or in Combination with Other Treatment Matthew Milowsky and Dean F. Bajorin Part III: TESTIS CANCER 28: Testis Cancer: Clinical Signs and Symptoms Timothy A. Masterson and Stephen D. W. Beck 29: The Epidemiology and Genetics of Sporadic and Hereditary Testicular Cancer David Vaughn, Kate Nathanson, and Peter Kanetsky 30: Biology and Genetics of Adult Male Germ Cell Tumors Darren R. Feldman, Jane Houldsworth, George J. Bosl, and R. S. K. Chaganti 31: Anatomy and Pathology of Testis Cancer Victor Reuter 32: Staging of Testicular Cancer 32A: Staging and Imaging in Germ Cell Tumors Brett S. Carver and Darren R. Feldman 32B: The Role of Serum Tumor Markers in the Diagnosis and Management of Testicular Cancer LaMont J. Barlow and James M. McKiernan 32C: Risk Assignment in Advanced Testis Cancer Dean F. Bajorin 33: Management of Low Stage Germ Cell Tumors of the Testis 33A: Management of Low-St