Chronic Obstructive Lung Disease

This clinical reference for practitioners offers a new and comprehensive look at chronic obstructive lung disease. Global in scale and importance, it is an important cause of morbidity and mortality. Bringing together a roster of internationally renowned contributors from the front lines of pulmonary medicine and research, it is aimed at practitioners in pulmonary medicine, pathology, thoracic radiology and epidemiology. Its focus is on the pathobiology of chronic obstructive pathology disease and emphysema and its exacerbation of chronic obstructive pulmonary disease and on treatment options. This reference works to 'connect the dots' by collating and centralizing the various data on the subject.


About the authors


Norbert F. Voelkel, MD Professor of Medicine, Director, Victoria Johnson Center for Emphysema Research Virginia Commonwealth University, School of Medicine Virginia
William MacNee, MBChB, MD, FRCPC, FRCPE Professor of Respiratory and Environmental Medicine Honorary Consultant Physician Patient Services Director, Respiratory Medicine University of Edinburgh Medical School, Teviot Place Edinburgh, Scotland






Table of contents


1: Chronic Bronchitis and Emphysema: Historical Overview
2: Lung Growth and Development
3: The Airway Epithelium
4: Epidemiology of COPD
5: Genetic Susceptibility and Development of Emphysema
6: Pediatric Obstructive Disease
7: Alpha-1 Antitrypsin Deficiency
8: Pathobiology of Chronic Bronchitis and Emphysema
9: Inflammation in the Pathogenesis of COPD
10: COPD - The Dutch Hypothesis
11: Environmental Factors of COPD
12: Hypersecretion
13: Surfactant and Small Airway Diseases
14: Diffuse Parenchymal Interstitial Lung in Small Airways
15: Other Large Airway Disease which Limit Airflow
16: Bacterial Infections and COPD
17: Viral Infections and COPD
18: Animal Models of Emphysema
19: The Physiology and Lung Function Analysis of Chronic Obstructive Airway Diseases
20: Imaging, Chest X-Ray, CT Scanning of Chronic Obstructive Lung Diseases
21: Bronchoscopy and Bronchography of Acute and Chronic Bronchitis
22: Ventilation/Perfusion Mismatch in COPD
23: Pulmonary Hypertension and Cor Pulmonale in COPD
24: The Clinical Management of Patients with COPD
25: Pharmacotherapy of COPD
26: Smoking Cessation
27: Respiratory Muscles in COPD
28: The "Acute Exacerbation" of COPD
29: COPD: A Wasting Disease
30: Surgical Treatment and Lung Transplantation in COPD
31: From COPD to Lung Cancer