Case-based Guide to Clinical Endocrinology

Written cases provide a thoughtful review of modern management and contemplation of the literature, much more so than even a case presentation without the patient. As a result, in recent years the written or prepared case has become the ideal forum for demonstrating how to manage a medical problem to the greatest benefit of the patient. In A Case-Based Guide to Clinical Endocrinology, distinguished clinicians provide stimulating instruction and insights into a wide variety of endocrine subjects, teaching readers modern management of the conditions described and offering targeted entry into the literature. Importantly, many of the important elements in the current curriculum for clinical endocrine training as recommended by the Association of Program Directors in Clinical Endocrinology, Diabetes and Metabolism are covered in this text. To reinforce learning and retention of knowledge, each author has also provided multiple choice questions following the case studies. Students, residents, fellows, and practitioners will find these examples to be an efficient way to review their understanding and increase their skills and abilities in patient investigation and management.

In all, A Case-Based Guide to Clinical Endocrinology offers a comprehensive volume of concise case-studies that will prove to be of significant importance to all clinicians practicing in this field.
Table of contents
Part I Pituitary


Introduction

Pam Freda, MD



Pituitary Apoplexy

Steven Jon Russell, MD and Karen Klahr Miller, MD


When and How to Withdraw Cabergoline Treatment in Microprolactinomas

Annamaria Colao, MD


Cushing’s Disease

Kawaljeet Kaur, MD and James W. Findlings, MD


Part II Thyroid Overactivity


Introduction

David Cooper, MD



Amiodarone-Induced Hyperthyroidism

Paul Aoun, MD and David Cooper, MD


Interferon-Induced Hyperthyroidism

Paul Aoun, MD and David Cooper, MD


Subclinical Hyperthyroidism Due to Multinodular Thyroid

Paul Aoun, MD and David Cooper, MD


Subacute (Dequervain’s) Thyroiditis

Paul Aoun, MD and David Cooper, MD


Part III Thyroid Underactivity


Introduction

Tony Weetman, MD



Amiodarone-Induced Hypothyroidism

Ramzi Ajjan, MD


Autoimmune Hypothyroidism with Persistent Elevation of TSH

Amit Allahabadia, MD


Hashimoto’s Thyroiditis and Type 1 Diabetes

Mark Vanderpump, MD


Part IV Thyroid Cancer


Introduction

Kenneth D. Burman, MD



Papillary Thyroid Cancer

Nicole Ehrhardt, MD and Victor Bernet, MD


Metastatic Papillary Thyroid Cancer

Henry B. Burch, MD


Medullary Thyroid Cancer

Jacqueline Jonklass, MD


Follicular Thyroid Carcinoma with Pulmonary and Osseous Metastases

Jason A. Wexler, MD and Kenneth D. Burman, MD




Part V Adrenal


Introduction

Lyn Loriaux, MD



Adrenal Insufficiency

Lyn Loriaux, MD


Case 2 NEED TITLE

Lyn Loriaux, MD


An Incidentally Discovered Adrenal Mass

Lyn Loriaux, MD


Part VI Hyperparathyroidism


Introduction

Simon Pearce, MD



Differentiation of primary hyperparathyroidism for familial benign

Hypocalciuric Hypercalcemia

Simon Pearce, MD


Management and Investigation of Acute Hypercalcemia

Simon Pearce, MD


Evaluation of Complex Primary Hyperparathyroidism

Simon Pearce, MD


Evaluation of Hypercalcemia in Infancy

R. Thomas, MD


Part VII Metabolic Bone Diseases


Introduction

Mone Zaidi, MD



Osteoporosis Due to Hormonal Withdrawal: Common Mistakes

Mone Zaidi, MD


Osteomalacia: A Cause of Biophosphonate Failure

Mone Zaidi, MD


Unusual Manifestation of Paget’s Disease of Bone

Mone Zaidi, MD


Solid Organ Transplantation, Chronic Renal Impairment and Skeletal

Complications

Mone Zaidi, MD


Part VIII Male Reproduction


Introduction

Stephen J. Winters, MD



Congenital Isolated Hypogonadotropic Hypogonadism

Stephen J. Winters, MD and Sathya Krishnasamy, MD


Klinefelter Syndrome

Stephen J. Winters, MD and Sathya Krishnasamy, MD


Low Testosterone in Obesity and Type 2 Diabetes

Stephen J. Winters, MD and Sathya Krishnasamy, MD



Part IX Female Reproduction


Introduction

Janet Hall, MD



Case 1

Janet Hall, MD, Sabrina Gill, MD, Corrine K. Welt, MD, Maria A. Yaimas, MD


Case 2

Janet Hall, MD, Sabrina Gill, MD, Corrine K. Welt, MD, Maria A. Yaimas, MD


Case 3

Janet Hall, MD, Sabrina Gill, MD, Corrine K. Welt, MD, Maria A. Yaimas, MD


Part X Pregnancy


Introduction

Alex Stagnaro-Green, MD



Hypertension in Pregnancy and Women with Child Bearing Potential

Lawrence R. Krakoff, MD


Hashimoto’s Hypothyroidism During Pregnancy

Susan J. Mandel, MD


Type 1 Diabetes Mellitus During Pregnancy

Carol Levy, MD and Gail Omry, MD


Part XI Type 1 Diabetes


Introduction

Ake Lernmark, MD


Part XII Type 2 Diabetes


Introduction

Barry Goldstein, MD



Exanatide in Type 2 Diabetes: Indications and Initiations

Venita Treat, MD and Serge Jabbour, MD


Case 2

Kevin Furlong, MD and Intekhab Ahmed, MD


Treatment of Type 2 Diabetes Mellitus with Oral Agents

Jeremy J. Flood, MD and Jeffrey L. Miller, MD


Part XIII Lipid Abnormalities


Introduction

Neil J. Stone, MD



Combination Drug Therapy in a Case of Severe Hypercholesterolemia

Neil J. Stone, MD


A Young Man with Abdominal Pain and Very High Triglycerides – The

Chyomicronemia

Neil J. Stone, MD


Roughly Equivalent Lipids in a Middle-Aged Obese Man at Risk for

Coronary Disease

Neil J. Stone, MD


Part XIV Obesity and the Metabolic Syndrome


Introduction

Robert Yanagisawa, MD and Derek LeRoith, MD



Metabolic Syndrome Case

Robert Yanagisawa, MD and Derek LeRoith, MD


The Polycystic Ovarian Syndrome

Michael Magnotti, MD and Walter Futterweit, MD


Bariatric Surgery Case

Robert Yanagisawa, MD, Daniel Henon, MD, and Derek LeRoith, MD


Part XV Puberty


Introduction

Donald Zimmerman, MD



A 16 ½ Years Old Female with Amenorrhea

Liuske Pesce, MD and Donald Zimmerman, MD


A 37 ½ Years Old Female with Early Puberty and Hyperthyroidism

Liuske Pesce, MD and Donald Zimmerman, MD


Hypothalamic Hamartoma

Liuske Pesce, MD and Donald Zimmerman, MD


Leydig Cell Adenoma

Liuske Pesce, MD and Donald Zimmerman, MD


Prolactinoma

Liuske Pesce, MD and Donald Zimmerman, MD


Turner Syndrome

Jami Josefson, MD


Part XVI Rarities That Teach


Introduction

Jeffrey Mechanik, MD



Hypothalamic Damage and Obesity

Lalita Khaodhiar, MD


Systemic Mastocytosis

Michael Kleerekoper, MD and Luis Afonso, MD


Testosteronoma

Kimberly E. Steele, MD and Martha A. Zeiger, MD.