Bethesda System for Reporting Thyroid Cytopathology

Thyroid fine needle aspiration is one of the most commonly performed cytologic procedures and is the standard diagnostic method for managing the patient with a thyroid nodule. Until now, there has been no uniform system for reporting the results of thyroid fine needle aspiration (FNA) in the U.S.

The terminology described in this book is an important advance in the field of cytopathology. It represents the results of the multidisciplinary National Cancer Institute Thyroid Fine Needle Aspiration State of The Science Conference, held in Bethesda, MD in October, 2007.

The Bethesda System for Reporting Thyroid Cytopathology will provide the reader with a unified approach to diagnosing and reporting thyroid FNA interpretations. It will serve as a reference guide not just for pathologists, but also endocrinologists, surgeons, and radiologists.

1 Overview of Diagnostic Terminology and Reporting by Zubair W. Baloch and Erik K. Alexander and Hassein Gharib and Stephen S. Raab 1
2 Nondiagnostic/Unsatisfactory by Barbara A. Crothers and Michael R. Henry and Pinar Firat and Ulrike M. Hamper 5
3 Benign by Tarik M. Elsheikh and Beatrix Cochand-Priollet and Pedro Patricio de Agustin and Mary K. Sidawy and Matthew A. Zarka 15
4 Atypia of Undetermined Significance/FoIlicular Lesion of Undetermined Significance by Jeffrey F. Krane and Ritu Nayar and Andrew A. Renshaw 37
5 Follicular Neoplasm/Suspicious for a Follicular Neoplasm by Michael R. Henry and Richard M. DeMay and Katherine Berezowski 51
6 Follicular Neoplasm, Hurthle Cell Type/Suspicious for a Follicular Neoplasm, Hiirthle Cell Type by William C. Paquin and Claire W. Michael and Andrew A. Renshaw and Philippe Vielh 59
7 Suspicious for Malignancy by elen H. Wang and Armando C. Filie and Douglas P. Clark and Celeste N. Powers 75
8 Papillary Thyroid Carcinoma and Variants by Manon Auger and Edward B. Stelow and Grace C. H. Yang and Miguel A. Sanchez and Sylvia L. Asa and Virginia A. Livolsi 91
9 Medullary Thyroid Carcinoma by Martha B. Pitman and Yolanda C. Oertel and Kim R. Geisinger 117
10 Poorly Differentiated Thyroid Carcinoma by Massimo Bongiovanni and William C. Faquin 129
11 Undifferentiated (Anaplastic) Carcinoma and Squamous Cell Carcinoma of the Thyroid by Gregg A. Staerkel and Britt-Marie E. Ljung and Vinod Sbidham and William J. Frable and Juan Rosai 139
12 Metastatic Tumors and Lymphomas by Lester J. Layfield and Jerry Waisman and Kristen A. Atkins 153
Index 167