Atlas of Peripheral Blood: The Primary Diagnostic Tool

This book will be a full-color atlas of both benign and neoplastic proliferations in the blood. The book will illustrate the morphologic features on peripheral blood smears of the various disorders and the text will focus on diagnostic criteria, differential diagnosis and modern classification terminology. The book may be used as a stand-alone resource and should be useful to trainees and clinicians that routinely review peripheral blood smears. The book will be accompanied by an on-line image bank containing numerous additional full-color images of the various disorders.

--Coverage of both benign and neoplastic proliferations in the blood
--Very comprehensive in regard to blood diseases, especially the red blood cell disorders
--Accompanied by an on-line image bank containing 500 additional full-color images of the various disorders

Irma Pereira MT (ASCP), SH

Clinical Hematology Specialist, Clinical Laboratories, Stanford University, Stanford, CA


Tracy I George MD

Assistant Professor of Pathology, Director, Clinical Hematology Laboratory, Stanford University Medical Center, Stanford, CA


Daniel A Arber MD

Professor and Vice Chair of Pathology, Medical Director, Anatomic Pathology and Clinical Laboratory Services, Department of Pathology, Stanford University, Stanford, CA

Preface

Contributors

Chapter 1 Introduction (Including smear methods, staining, features of the normal blood smear and the approach to interpretation)

Section 1 Red Blood Cells and Their Disorders
Chapter 2 Common Red Cell Changes/Nomenclature (Targets, Schistocytes, Spherocytes, etc)
Chapter 3 Anemia Due to Abnormal or Impaired Hemoglobin Synthesis
Defects in iron metabolism
Defects in porphyrin synthesis
Defects in globin chains, including thalassemias
Chapter 4 Anemia Dues to Abnormal or Impaired DNA Synthesis
Anemias with oval macrocytosis
Megaloblastic Anemia
Myelodysplastic Syndrome
Congenital dyserythropoietic anemia
Anemias with round macrocytosis
Reticulocytosis
Liver disease
Alcoholism
Chapter 5 Hemolytic Anemias
Extracorpuscular
Microangiopathic anemia
Oxidative hemolytic anemia
Autoimmune hemolytic anemia
Heat-associated and other traumatic anemias
Intracorpuscular (Membrane defects)
Congenital spherocytosis
Congenital ovalocytosis
Pyropoikilocytosis
Hemolytic Ovalocytosis
Congenital Acanthocytosis
a-betalipoprotinemia
Acquired Acanthocytosis
Alcoholic cirrhosis
Liver disease/tumors
Anorexia nervosa
Prematurity
Unstable hemoglobins

Section 2 Granulocytes and Their Disorders
Chapter 6 Reactive Changes in Granulocytes and Monocytes
Chapter 7 Systemic Disorders with Granulocyte and Monocyte Inclusions
Chediak-Higashi granules
May Hegglin anomaly
Mucopolysaccaridosis/Alder Reilly granules
Morquio syndrome
Hurler syndrome
Wiskott Aldridge syndrome
Chapter 8 Chronic Myeloproliferative Disorders
Chronic myelogenous leukemia
Chronic phase
Accelerated phase
Blast phase
Polycythemia vera
Chronic idiopathic myelofibrosis
Essential thrombocythemia
Chronic neutrophilic leukemia
Chronic eosinophilic leukemia and hypereosinophilic syndrome
Mast cell disease
Chronic myeloproliferative disorders, unclassifiable
Chapter 9 Myelodysplastic Syndromes and Related Entities
Myelodysplastic features in the blood
Pelger-Huet anomaly
Drug effects mimicking myelodysplasia
Chapter 10 Myeloproliferative/Myelodysplastic Diseases
Chronic myelomonocytic leukemia
Atypical chronic myeloid leukemia
Juvenile myelomonocytic leukemia
Mixed myeloproliferative/myelodysplastic disease, unclassifiable
Chapter 11 Acute Myeloid Leukemia
AML, not otherwise categorized subtypes
AML with t(8;21)
AML with inv(16)
Acute promyelocytic leukemia (AML with t(15;17) and variants)
AML with other cytogenetic abnormalities
AML with multilineage dysplasia
Therapy-related AML and myelodysplasia
Chapter 12 Acute Leukemia of Ambiguous Lineage
Acute undifferentiated leukemia
Biphenotypic acute leukemia
Bilineal acute leukemia

Section 3 Lymphocytes and Their Disorders
Chapter 13 Reactive Lymphocytes
Infectious mononucleosis
Others (other viral infections, large granular lymphocytes and pertussis)
Chapter 14 Precursor Lymphoid Malignancies
Precursor B-lymphoblastic leukemia
Precursor T-lymphoblastic leukemia
Chapter 15 Mature Small B-cell Neoplasms Involving the Blood
Chronic lymphocyte leukemia
Usual Type
Atypical CLL

Abbreviated Table of Contents